ANTI-BAX ANTIBODY PRODUCED IN RABBIT

Code: SAB5700002-100UL D2-231

General description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regu...


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General description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BAX (NP_620116.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
concentration1.09 mg/ml
formbuffered aqueous solution
Gene Informationhuman ... BAX(581)
mol wt12, 21, 4 kDa, 19, 24, 15, 18
Quality Level100
shipped inwet ice
species reactivityhuman, mouse, rat
storage temp.−20°C
technique(s)immunohistochemistry: 1:50-1:100, immunofluorescence: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.Q07812
This product has met the following criteria to qualify for the following awards:



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